The accidents, witnessed said, occurred at Alumorufu in Iyana-Ipaja along the Lagos-Abeokuta Expressway.
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From videos posted on the social media, most of the injured were all bloodied as onlookers tried to rescue more persons feared trapped underneath affected vehicles.
Although details of the crash were still not clear, witnesses said a baby and a man were among those who died.
The Nation gathered about 10 vehicles were involved in the accident. At the time of this report, neither the Lagos State Emergency Management Agency (LASEMA) nor other stakeholders were at the scene.