Why some people are unable to contact Ebola disease – Experts

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ebolaFollowing news survival some the workers who contracted Ebola virus from Patrick Sawyer, Experts have said that some people are able survive the due the workings their immune . according research, some people have immune systems that prevent the altogether.

According to reports:

“Doctors don’t know for certain who survive Ebola, and there is no specific treatment or cure for the . But studies suggest there are some biological markers linked with a higher chance surviving Ebola,” the experts say.

the view of Derek Gatherer, a Bioinformatics researcher at Lancaster University the Kingdom, who studies viral genetics and evolution, “when a person becomes infected with Ebola, the virus depletes the body’s immune cells, which defend against infection.

particular, the Ebola virus depletes immune cells called CD4 and CD8 T lymphocytes, which are crucial to the function of the immune ”, Gatherer noted, arguing that “if a person’s immune can stand up to this initial attack — meaning their immune cells are as depleted in the first stages of infection — then they are more likely to survive the disease.

“The patients that survive it best are the ones who don’t such a bad immune deficiency. But if the body is able to fend off this attack, then the immune becomes less able to regulate itself”, Gatherer said. [eap_ad_2] Another marker linked with people’s ability to survive Ebola is a gene called human leukocyte antigen-B, which makes a protein that is important in the immune . A 2007 study found that people with certain versions of this gene, called B*07 and B*14, were more likely to survive Ebola, while people with other versions, called B*67 and B*15, were more likely to die.

Some people may be resistant to Ebola infection entirely, if they have a mutation in a gene called NPC1. Studies show that, when researchers take cells from people with the NPC1 mutation and try to infect them with Ebola in a laboratory dish, these cells are resistant to the virus.

Gatherer said in European populations, about 1 in 300 to 1 in 400 people has this mutation.

“But in some populations, this mutation is more common: in Nova Scotia, between 10 and 26 per cent of people have this mutation. But the frequency of this mutation in African populations is known,” he said.

Also giving an insight, Lagos state Babatunde remarked: “This is a virus that run a maximum of 21 days. What we must do is people who show some signs of illness should come in very early so that we can continue to hydrate them, give electrolyte balance so that their nervous system do not go into shock and wherever it is necessary to antibiotics for patients; and their body can fight the virus which in the event last no longer than 21 days.”[eap_ad_3]