Blasio told CNN on Monday morning that he would visit a hospital later in the day to witness a healthcare worker receive the first shots.
He stated that the vaccine offered hope to the city, “and New Yorkers could now see the light at the end of the tunnel”.
“It is going to be a good day,” the mayor said.
He was not specific on the number of doses that arrived on Monday, but reports say officials were expecting enough to vaccinate 170,000 people.
This represents a quarter of the estimated 1.8 million people on the priority list in the first phase of inoculation in the state, reports say.
Monday’s shipment is part of the state’s initial allocation, and priority will be given to people considered most at risk as is the case nationwide.
The first groups to be inoculated will be frontline healthcare workers, and staff members, and residents of nursing homes and long-term care facilities.
The News Agency of Nigeria (NAN) reports that New York was the hardest-hit state in the U.S. during the first wave of the pandemic.
According to John Hopkins University, total infections and fatalities in the state were no fewer than 775,160 and 35,557, respectively.
The vaccine’s arrival came at a time the state is experiencing a resurgence of infections, which are increasing by no fewer than 10,000 daily.
New York is also currently recording a daily death increase by 107, as hospitals get flooded by patients in numbers last seen in May.
Soon after the U.S. Food and Drugs Administration (FDA) approved the vaccine on Friday, Gov. Andrew Cuomo said the state was ready for distribution.
Cuomo said the state government had prepared the necessary groundwork for “the most aggressive distribution administration programme”.
“The vaccine is coming and we’re ready to administer it,” he said.